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2025-05-20Novel Cuproptosis-Inhibitory Triketone-sesquiterpene Conjugates Corymbinols A and B from the Fruits of Corymbia citriodoraCorymbinols A (1) and B (2a/2b), novel bis-β-triketone hybrids fused with sesquiterpene and chalcone units, were isolated from Corymbia citriodora fruits. Corymbinols A inhibited cuproptosis in HepG2 cells by 31% at the concentration of 20 μM, implying the potential as a non-toxic therapeutic against liver vancer. Corymbinols A (1) and B (2a/2b), novel bis-β-triketone hybrids fused with sesquiterpene and chalcone units, were isolated from Corymbia citriodora fruits. Corymbinols A 1 inhibited cuproptosis in HepG2 cells by 31% at the concentration of 20 μM, implying the potential as a non-toxic therapeutic against liver vancer.Cuproptosis, a recently ide...Read More -
2025-05-20Spatial Differentiation of Glomalin-Related Soil Proteins in Tropical Montane RainforestsGRSP and GRSP/SOC exhibited strong spatial autocorrelation, with contrasting topographic trends: GRSP peaked in ridges but was lowest in valleys, whereas GRSP/SOC was highest in valleys. Soil total nitrogen, available phosphorus, and pH were key predictors of GRSP in ridges, while pH was the critical predictor of GRSP/SOC in valleys. A research team from the South China Botanical Garden (SCBG) of the Chinese Academy of Sciences has uncovered the spatial variation patterns of glomalin-related soil proteins (GRSP) in tropical montane rainforests and their contribution mechanisms to soil organic carbon (SOC). The study, conducted in the 60-hectare Jianfengling tropical montane ...Read More -
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2025-05-09Plant Traits Remain Stable After 18 Years of Nitrogen Addition in a Tropical ForestAn 18-year nitrogen (N) addition experiment in a tropical nitrogen-saturated forest reveals that plant morphological and physiological traits remain largely stable across trees, shrubs, and herbs. Leaf traits better distinguish plant functional groups than root traits, and nutrient acquisition strategies indicated by leaf or root economics spect... As global atmospheric nitrogen deposition intensifies, its ecological impact on nitrogen-limited regions is well-documented. However, how prolonged nitrogen inputs affect plant functional traits in already nitrogen-saturated ecosystems remains uncertain. To explore this, researchers from the South China Botanical Garden, Chinese Academy of Scien...Read More -
2025-04-29Taxonomic Diversity Predicts Aboveground Biomass Mainly Through Functional Dominance Across Subtropical Forest SuccessionSCBG scientists investigated how taxonomic diversity influences tree aboveground biomass during subtropical forest succession. Their findings reveal that taxonomic diversity affects biomass mainly indirectly through its impact on functional properties, particularly functional dominance, highlighting the critical role of species with key function... Understanding how taxonomic diversity influences forest aboveground biomass is crucial for sustaining ecosystem services and functioning, especially in the context of global biodiversity loss. Although manipulative experiments have shown that both functional diversity and functional dominance contribute to biomass production, with functional div...Read More -
2025-04-23Bellidifolin from Swertia diluta Improves High-Fat Diet-Induced Obesity via Gut Microbiota and Bile Acid RegulationBellidifolin (BEL) isolated from Swertia diluta has been demonstrated significant efficacy in mitigating high-fat diet-induced obesity and dyslipidemia in a mice model. This effect is mediated through modulation of gut microbiota composition and enhancement of bile acid biosynthesis and excretion, resulting in improved lipid metabolic profiles. Obesity and related metabolic disorders, including hyperlipidemia and non-alcoholic fatty liver disease, have become significant global public health challenges. According to the World Health Organization, the worldwide obesity rate has nearly tripled since 1975, affecting approximately 650 million adults. High-fat diet (HFD) is a key driver of ...Read More -
2025-04-23Recent Advances in Pan-genome Analysis of Forest TreesPan-genome data have been utilized to explore the genetic basis of adaptation, but such studies remain limited in forest trees. Here, the authors constructed the first pan-genome of Quercus variabilis and demonstrated how introgression facilitates local adaptation in oak species. Understanding the genetic basis of local adaptation is a crucial question in evolutionary biology. Previous studies, relying on single reference genomes and short-read sequencing, have struggled to comprehensively resolve structural variants (SVs) — large-scale genomic alterations proven to regulate stress-response genes and drive phenotypic di...Read More